What is Bis(trichloromethyl)carbonate?

Bis(trichloromethyl)carbonate is chemical substance, CSA number is 32315-10-9, molecular formula is C3Cl6O3. commonly known as trigluminescence (hereinafter referred to as BTC), is a stable white crystal, melting point 79~81 degrees, the compound was synthesized by German chemist Counder in 1880, and its physical and chemical properties were first reported in 1887, while its solid state structure was The solid state structure was only publicly reported in 1971. Since its molecular structure contains carbonyl and trichloromethyl groups, it has a variety of chemical reaction properties and can be utilized for a variety of reactions. A large number of reports have been made in the last decade. BTC has been successfully used to replace phosgene in the synthesis of new polymer materials, pharmaceuticals, pesticides and other reactions.

 

 

Applications of BTC in organic synthesis

 

●Nucleophilic substitution reactions

Under the action of auxiliary nucleophiles, one molecule of BTC can produce three molecules of active intermediates, which can react with various nucleophiles under mild conditions.

 

● Reaction of BTC with carbon nucleophile

 

●Reaction of BTC with nitrogen nucleophile

 

●Ring formation reaction of BTC with binuclear nucleophiles

 

●Chlorination reaction

 

●Swern oxidation reaction

 

●Isonitriles reaction

 

As an alternative to phosgene and diphosgene, BTC has the advantages of safety and economy, ease of use, accurate reaction measurement, mild conditions, good product quality and high yield, which can avoid the danger arising from improper use of phosgene. At present, the process of preparing dimethyl carbonate from methanol and carbon monoxide is maturing, and the price of industrialized products is getting lower and lower, so the cost of preparing BTC is not too high.

 

In addition, methanol cyclic chlorination method can realize the mass production of cheap BTC, which will promote the wider application of BTC in organic synthesis.

 

Hebei Boze Chemical Co., Ltd, established in 2013 with a registered capital of 30 million, is a large-scale production and export-oriented enterprise Boze offers high purity bis(trichloromethyl) carbonate at the right price, welcome to inquire!

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